N. Viazis, F. Albani, A. Mountaki, K. Koustenis, C. Veretanos, A. Tsatsa, A. Trikola, E. Beka, K. Arvanitis, T. Georgiadi, G. Karabekos, E. Vienna, E. Archavlis, M. Mela, A. Christidou, Ch. Chatzievangelinou, K. Katopodi, V. Papastergiou, G. J. Mantzaris
Gastroenterology Department, Evangelismos General Hospital, Athens – Greece
Global Journal of Gastroenterology & Hepatology Research [GJGHR]
Aim: Small bowel capsule endoscopy (SBCE) is a valuable diagnostic tool used for a variety of clinical indications. Using a large database, we aimed at evaluating indications and diagnostic yield of SBCE in a real-world setting.
Methods: Retrospective analysis of a prospectively-stored database, including all patients who underwent SBCE over a 18-year period (3/2003-11/2021). Depending on the indication, patients were divided into 3 groups: group A = investigation of obscure gastrointestinal bleeding (overt or occult), group B = investigation of patients with diagnosed or probable Crohn’s disease and group C = all other indications. Diagnostic yield was defined as tests with positive findings that could explain the patient’s symptoms and the indication for SBCE referral.
Results: Overall, 7501 patients were included (men/women: 3860/3641, mean age ± SD: 52.6±27.3 years). The most common indication was obscure gastrointestinal bleeding (group A, n= 4012, 53.4%) followed by diagnosed or probable Crohn’s disease (group B, n = 2557, 34.1%) and all other indications (group C, n = 932, 12.4%). The diagnostic yield of SBCE was 40.4% for group A, 63.4% for group B and 26.4% for group C. The most common finding in group A was angiodysplasia (n=1253, 31.2%), in group B lesions compatible with Crohn’s disease (n=1392, 54.4%) and in group C ulcers from aspirin and NSAIDs (n=91, 9.7%).
Conclusion: Indications of SBCE in a real-world setting are largely consistent with current guidelines. The diagnostic yield of SBCE varies considerably depending on the indication, ranging from 26% to 63%.
Tags
Crohn’s and Colitis Journals | Gastroenterology & Hepatology Journals | Gastroenterology Journals | Research Gastroenterology and Hepatology Journals | Clinical and Experimental Gastroenterology Journals | Gastrointestinal Endoscopy Journals | Therapeutic Advances in Gastroenterology Journals | Colorectal Disease: clinical and molecular gastroenterology and surgery Journals | Inflammatory Bowel Diseases Journals | Expert Review of Gastroenterology & Hepatology Journals | Clinical Colorectal Journals | Cancer Gut Journals | Endoscopy Journals | Hepatitis B Annual Journals | Hepato-biliary-Pancreatic Sciences Journals | Medical Bulletin Journals
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