Association between signs of hyperalgesia and reported frequent pain in jaw-face and head

Dr. Negin Yekkalam

Abstract: Introduction: Temporomandibular disorder (TMD) is a term that refers to a number of painful and non-painful disorders that affect the muscles of mastication, the temporomandibular joint and contiguous structures. Ehlers-Danlos syndrome (EDS) is a heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility and cutaneous hyperextensibility and fragility. Despite the fact of EDS being a risk factor for TMD, lack of diagnosis and inadequate care have been reported as reasons why patients have negative impressions toward dental care and health care systems. Therefore, the prevalence of TMD as well as the treatment need for TMD among individuals with EDS are still unknown. The aim of this study was to assess the received TMD treatment modalities and the perceived outcome among the frequent types of EDS. A digital questionnaire was sent to the member of the National Swedish EDS Association during January-March 2022. The subsamples of hypermobile EDS (hEDS) and classical EDS (cEDS) were constructed. Almost 90% reported TMD symptoms. Bite splint therapy, counselling, jaw training and occlusal adjustment were reported as the most common treatments with no statistically significant difference in terms of good effect between the two subsamples. Hypermobile and classical EDS might consider as an entity with regards to TMD. Keywords: Temporomandibular disorders, Ehlers-Danlos syndrome, hypermobility, occlusal adjustment

Digital Formats: Variant prioritization, gene-phenotype associations, NGS data analysis, precision diagnostics

Figure 2. Different treatment modalities for TMD and Good
subjective effect of the received treatments amo

References: [1] Dworkin SF, LeResche L.(1992) J Craniomandib Disord.;6(4):301–355. [2] National Institute of Dental and Craniofacial Research. Facial Pain. Available from https://www.nidcr.nih.gov/ research/data-statistics/facial-pain. [3] Hirsch C, John MT, Stang A. (2008) Eur J Oral Sci. 116 (6):525–30. [4]Westling L. (1992) Swed Dent J Suppl. 1992;81:1–79. [5] Kapferer-Seebacher I, Lundberg P, Malfait F, et al. (2017) J Clin Periodontol. 44(11):1088–1100. [6] Berglund B, Nordström G. (2001) J Clin Rheumatol. 7(5):308–314. [7] Mitakides JE. (2018) Cranio.36 (2):71–72. [8] Ilgunas A, Wänman A, Strömbäck M.(2020). Eur J Oral Sci. 128(1):74– 80. [9] Yekkalam N, Wänman A. (2021) Acta Odontol Scand. 79(3):188–93. [10] Camerota F, Celletti C, Castori M, et al. (2011) J Pain Symptom Manage. 41(1):e2–4. 41. [11] Chopra P, Tinkle B, Hamonet C, et al. (2017) Am J Med Genet C Semin Med Genet. [12] Nationella riktlinjer för vuxentandvård 2011 [Available from: http://www.socialstyrelsen.se/tand vardsriktlinjer].

Biography: Negin Yekkalam Balfe is specialist dentist within orofacial pain and temporomandibular disorders from Sweden. She has completed her PhD within temporomandibular disorders in different perspectives such as epidemiology, etiology, treatment needs, and pain comorbidities, from Umeå University, Sweden. She has also accomplished a Master degree within ’’epidemiology’’ from Umeå university as well as a Master degree within ‘’experimental orofacial pain’’ from Karolinska institute, Stockholm, Sweden. Her main research area is epidemiological studies within oral health, and comorbidities with TMD. Currently she is the principal investigator (PI) for the EDS project in Sweden and Finland. This project is focusing on TMD in different perspectives among EDS population and has a strong collaboration with experts from Europe and the USA. She is the member of Swedish association of orofacial pain, and Swedish Pain Society. She has published 11 articles in highimpact journals.

Upcoming UCG Conference;

Exit mobile version